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The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program “CASCADE”

BACKGROUND: Understanding the cancer genome is seen as a key step in improving outcomes for cancer patients. Genomic assays are emerging as a possible avenue to personalised medicine in breast cancer. However, evolution of the cancer genome during the natural history of breast cancer is largely unkn...

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Detalles Bibliográficos
Autores principales: Savas, Peter, Teo, Zhi Ling, Lefevre, Christophe, Flensburg, Christoffer, Caramia, Franco, Alsop, Kathryn, Mansour, Mariam, Francis, Prudence A., Thorne, Heather A., Silva, Maria Joao, Kanu, Nnennaya, Dietzen, Michelle, Rowan, Andrew, Kschischo, Maik, Fox, Stephen, Bowtell, David D., Dawson, Sarah-Jane, Speed, Terence P., Swanton, Charles, Loi, Sherene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189956/
https://www.ncbi.nlm.nih.gov/pubmed/28027312
http://dx.doi.org/10.1371/journal.pmed.1002204