Experimental Estimation of the Effects of All Amino-Acid Mutations to HIV’s Envelope Protein on Viral Replication in Cell Culture

HIV is notorious for its capacity to evade immunity and anti-viral drugs through rapid sequence evolution. Knowledge of the functional effects of mutations to HIV is critical for understanding this evolution. HIV’s most rapidly evolving protein is its envelope (Env). Here we use deep mutational scan...

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Detalles Bibliográficos
Autores principales: Haddox, Hugh K., Dingens, Adam S., Bloom, Jesse D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189966/
https://www.ncbi.nlm.nih.gov/pubmed/27959955
http://dx.doi.org/10.1371/journal.ppat.1006114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189966/
https://www.ncbi.nlm.nih.gov/pubmed/27959955
http://dx.doi.org/10.1371/journal.ppat.1006114

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