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A novel synthetic Asiatic acid derivative induces apoptosis and inhibits proliferation and mobility of gastric cancer cells by suppressing STAT3 signaling pathway

Activation of the transcription factor, signal transducers and activators of transcription 3 (STAT3), has been linked to the proliferation and migration of a variety of human cancer cells. These actions occur via the upregulation or downregulation of cell survival and tumor suppressor genes, respect...

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Detalles Bibliográficos
Autores principales: Wang, Gang, Jing, Yue, Cao, Lingsen, Gong, Changchang, Gong, Zhunan, Cao, Xiangrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189974/
https://www.ncbi.nlm.nih.gov/pubmed/28053540
http://dx.doi.org/10.2147/OTT.S121619