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Combination of radiotherapy and vaccination overcomes checkpoint blockade resistance

The majority of cancer patients respond poorly to either vaccine or checkpoint blockade, and even to the combination of both. They are often resistant to high doses of radiation therapy as well. We examined prognostic markers of immune cell infiltration in pancreatic cancer. Patients with low CD8(+)...

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Detalles Bibliográficos
Autores principales: Zheng, Wenxin, Skowron, Kinga B., Namm, Jukes P., Burnette, Byron, Fernandez, Christian, Arina, Ainhoa, Liang, Hua, Spiotto, Michael T., Posner, Mitchell C., Fu, Yang-Xin, Weichselbaum, Ralph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190006/
https://www.ncbi.nlm.nih.gov/pubmed/27343548
http://dx.doi.org/10.18632/oncotarget.9915