Epithelial ovarian cancer-secreted exosomal miR-222-3p induces polarization of tumor-associated macrophages

Cancer secreted exosomal miRNAs are emerging as mediators between tumor-stoma crosstalk. Here, we show epithelial ovarian cancer (EOC)-derived exosomes activated macrophages to a tumor-associated macrophage (TAM)-like phenotype with SOCS3/STAT3 pathway involvement, which could facilitate the progres...

Descripción completa

Detalles Bibliográficos
Autores principales: Ying, Xiang, Wu, Quanfeng, Wu, Xiaoli, Zhu, Qinyi, Wang, Xinjing, Jiang, Lu, Chen, Xin, Wang, Xipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190009/
https://www.ncbi.nlm.nih.gov/pubmed/27172798
http://dx.doi.org/10.18632/oncotarget.9246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190009/
https://www.ncbi.nlm.nih.gov/pubmed/27172798
http://dx.doi.org/10.18632/oncotarget.9246

Ejemplares similares