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Orai1 promotes tumor progression by enhancing cancer stemness via NFAT signaling in oral/oropharyngeal squamous cell carcinoma

Emerging evidence indicates that Orai1, a key calcium channel for store-operated Ca(2+) entry, is associated with human cancer. However, the underlying mechanism by which Orai1 regulates cancer progression remains unknown. Here we report that intracellular level of Orai1 is increased in a stepwise m...

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Detalles Bibliográficos
Autores principales: Lee, Sung Hee, Rigas, Nicole Kristina, Lee, Chang-Ryul, Bang, April, Srikanth, Sonal, Gwack, Yousang, Kang, Mo K., Kim, Reuben H., Park, No-Hee, Shin, Ki-Hyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190020/
https://www.ncbi.nlm.nih.gov/pubmed/27259269
http://dx.doi.org/10.18632/oncotarget.9755