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Sirt3-mediated mitophagy protects tumor cells against apoptosis under hypoxia

Sirt3, a mitochondrial deacetylase, participates in the regulation of multiple cellular processes through its effect on protein acetylation. The objective of this study was to explore the role of Sirt3 in the mitochondrial autophagy (mitophagy), a process of the specific autophagic elimination of da...

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Detalles Bibliográficos
Autores principales: Qiao, Aimin, Wang, Kuansong, Yuan, Yunsheng, Guan, Yidi, Ren, Xingcong, Li, Lanya, Chen, Xisha, Li, Feng, Chen, Alex F., Zhou, Jianda, Yang, Jin-Ming, Cheng, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190031/
https://www.ncbi.nlm.nih.gov/pubmed/27270321
http://dx.doi.org/10.18632/oncotarget.9717