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HIF2α/EFEMP1 cascade mediates hypoxic effects on breast cancer stem cell hierarchy

Breast cancer stem cells (BCSCs) have been shown to contribute to tumor growth, metastasis, and recurrence. They are also markedly resistant to conventional cancer treatments, such as chemotherapy and radiation. Recent studies have suggested that hypoxia is one of the prominent micro-environmental f...

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Detalles Bibliográficos
Autores principales: Kwak, Ji-Hye, Lee, Na-Hee, Lee, Hwa-Yong, Hong, In-Sun, Nam, Jeong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190041/
https://www.ncbi.nlm.nih.gov/pubmed/27270657
http://dx.doi.org/10.18632/oncotarget.9846