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Blocking the PAH2 domain of Sin3A inhibits tumorigenesis and confers retinoid sensitivity in triple negative breast cancer

Triple negative breast cancer (TNBC) frequently relapses locally, regionally or as systemic metastases. Development of targeted therapy that offers significant survival benefit in TNBC is an unmet clinical need. We have previously reported that blocking interactions between PAH2 domain of chromatin...

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Detalles Bibliográficos
Autores principales: Bansal, Nidhi, Bosch, Almudena, Leibovitch, Boris, Pereira, Lutecia, Cubedo, Elena, Yu, Jianshi, Pierzchalski, Keely, Jones, Jace W., Fishel, Melissa, Kane, Maureen, Zelent, Arthur, Waxman, Samuel, Farias, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190053/
https://www.ncbi.nlm.nih.gov/pubmed/27286261
http://dx.doi.org/10.18632/oncotarget.9905