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Blocking the PAH2 domain of Sin3A inhibits tumorigenesis and confers retinoid sensitivity in triple negative breast cancer
Triple negative breast cancer (TNBC) frequently relapses locally, regionally or as systemic metastases. Development of targeted therapy that offers significant survival benefit in TNBC is an unmet clinical need. We have previously reported that blocking interactions between PAH2 domain of chromatin...
Autores principales: | Bansal, Nidhi, Bosch, Almudena, Leibovitch, Boris, Pereira, Lutecia, Cubedo, Elena, Yu, Jianshi, Pierzchalski, Keely, Jones, Jace W., Fishel, Melissa, Kane, Maureen, Zelent, Arthur, Waxman, Samuel, Farias, Eduardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190053/ https://www.ncbi.nlm.nih.gov/pubmed/27286261 http://dx.doi.org/10.18632/oncotarget.9905 |
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