Redox-sensitive MAPK and Notch3 regulate fibroblast differentiation and activation: a dual role of ERK1/2

Myofibroblastic transformation, characterized by upregulation of α-smooth muscle actin in response to profibrotic agents such as TGF-β1, is considered as a major event leading to fibrosis. The mechanistic basis linking myofibroblast differentiation to idiopathic pulmonary fibrosis and the disease tr...

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Detalles Bibliográficos
Autores principales: Lai, Jun-Mei, Zhang, Xiong, Liu, Fang-Fang, Yang, Rui, Li, Shen-Yu, Zhu, Lan-Bing, Zou, Ming, Cheng, Wen-Hsing, Zhu, Jian-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190056/
https://www.ncbi.nlm.nih.gov/pubmed/27248323
http://dx.doi.org/10.18632/oncotarget.9667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190056/
https://www.ncbi.nlm.nih.gov/pubmed/27248323
http://dx.doi.org/10.18632/oncotarget.9667

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