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Redox-sensitive MAPK and Notch3 regulate fibroblast differentiation and activation: a dual role of ERK1/2
Myofibroblastic transformation, characterized by upregulation of α-smooth muscle actin in response to profibrotic agents such as TGF-β1, is considered as a major event leading to fibrosis. The mechanistic basis linking myofibroblast differentiation to idiopathic pulmonary fibrosis and the disease tr...
Autores principales: | Lai, Jun-Mei, Zhang, Xiong, Liu, Fang-Fang, Yang, Rui, Li, Shen-Yu, Zhu, Lan-Bing, Zou, Ming, Cheng, Wen-Hsing, Zhu, Jian-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190056/ https://www.ncbi.nlm.nih.gov/pubmed/27248323 http://dx.doi.org/10.18632/oncotarget.9667 |
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