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AKR1B10 promotes breast cancer metastasis through integrin α5/δ-catenin mediated FAK/Src/Rac1 signaling pathway

Aldo-keto reductase 1B10 (AKR1B10) is not expressed in normal breast, but upregulated in primary and metastatic breast cancers, being a negative prognostic factor. This study characterized the molecular mechanisms of AKR1B10-promoted breast cancer metastasis. Ectopic expression of AKR1B10 in breast...

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Detalles Bibliográficos
Autores principales: Huang, Chenfei, Verhulst, Steven, Shen, Yi, Bu, Yiwen, Cao, Yu, He, Yingchun, Wang, Yuhong, Huang, Dan, Cai, Chun, Rao, Krishna, Liao, Duan-Fang, Jin, Junfei, Cao, Deliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190059/
https://www.ncbi.nlm.nih.gov/pubmed/27248472
http://dx.doi.org/10.18632/oncotarget.9672