IRE1α inhibition by natural compound genipin on tumour associated macrophages reduces growth of hepatocellular carcinoma

Accumulating evidences postulated the influential roles of macrophages in mediating hepatocellular carcinoma (HCC) initiation and progression. In this study, we demonstrate that a small molecule, genipin reduced HCC growth through suppressing IRE1α-mediated infiltration and priming of tumour associa...

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Detalles Bibliográficos
Autores principales: Tan, Hor-Yue, Wang, Ning, Tsao, Sai-Wah, Che, Chi-Ming, Yuen, Man-Fung, Feng, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190060/
https://www.ncbi.nlm.nih.gov/pubmed/27270308
http://dx.doi.org/10.18632/oncotarget.9696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190060/
https://www.ncbi.nlm.nih.gov/pubmed/27270308
http://dx.doi.org/10.18632/oncotarget.9696

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