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IRE1α inhibition by natural compound genipin on tumour associated macrophages reduces growth of hepatocellular carcinoma
Accumulating evidences postulated the influential roles of macrophages in mediating hepatocellular carcinoma (HCC) initiation and progression. In this study, we demonstrate that a small molecule, genipin reduced HCC growth through suppressing IRE1α-mediated infiltration and priming of tumour associa...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190060/ https://www.ncbi.nlm.nih.gov/pubmed/27270308 http://dx.doi.org/10.18632/oncotarget.9696 |