Cargando…

Long noncoding RNA RP11-838N2.4 enhances the cytotoxic effects of temozolomide by inhibiting the functions of miR-10a in glioblastoma cell lines

Resistance to temolozomide (TMZ), the standard chemotherapy agent for treating glioblastomas (GBM), is a major clinical problem for patients with GBM. Recently, long noncoding RNAs (lncRNAs) have been implicated in chemotherapy resistance in various cancers. In this study, we found that the level of...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yanting, Xu, Ningbo, Liu, Boyang, Huang, Yiru, Zeng, Huijun, Yang, Zhao, He, Zhenyan, Guo, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190063/
https://www.ncbi.nlm.nih.gov/pubmed/27270310
http://dx.doi.org/10.18632/oncotarget.9699