Demonstration of potential link between Helicobacter pylori related promoter CpG island methylation and telomere shortening in human gastric mucosa

BACKGROUND: Telomere length shortening in Helicobacter pylori (H. pylori) infected gastric mucosa constitutes the earliest steps toward neoplastic transformation. In addition to this genotoxic changes, epigenetic changes such as promoter CpG island (PCGI) methylation are frequently occurred in H. py...

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Detalles Bibliográficos
Autores principales: Tahara, Tomomitsu, Shibata, Tomoyuki, Okubo, Masaaki, Kawamura, Tomohiko, Horiguchi, Noriyuki, Ishizuka, Takamitsu, Nakano, Naoko, Nagasaka, Mitsuo, Nakagawa, Yoshihito, Ohmiya, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190073/
https://www.ncbi.nlm.nih.gov/pubmed/27259265
http://dx.doi.org/10.18632/oncotarget.9764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190073/
https://www.ncbi.nlm.nih.gov/pubmed/27259265
http://dx.doi.org/10.18632/oncotarget.9764

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