UCN-01 enhances cytotoxicity of irinotecan in colorectal cancer stem-like cells by impairing DNA damage response

Colorectal cancer (CRC) is one of the most common and lethal cancers worldwide. Despite recent progress, the prognosis of advanced stage CRC remains poor, mainly because of cancer recurrence and metastasis. The high morbidity and mortality of CRC has been recently ascribed to a small population of t...

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Detalles Bibliográficos
Autores principales: Signore, Michele, Buccarelli, Mariachiara, Pilozzi, Emanuela, De Luca, Gabriele, Cappellari, Marianna, Fanciulli, Maurizio, Goeman, Frauke, Melucci, Elisa, Biffoni, Mauro, Ricci-Vitiani, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190083/
https://www.ncbi.nlm.nih.gov/pubmed/27286453
http://dx.doi.org/10.18632/oncotarget.9859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190083/
https://www.ncbi.nlm.nih.gov/pubmed/27286453
http://dx.doi.org/10.18632/oncotarget.9859

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