Silencing DNA methyltransferase 1 (DNMT1) inhibits proliferation, metastasis and invasion in ESCC by suppressing methylation of RASSF1A and DAPK

Our previous study showed DNMT1 is up-regulated in esophageal squamous cell carcinoma (ESCC), which is associated with methylation of tumor suppressors. In the current study, we investigate the role of DNMT1 in ESCC. We found silencing DNMT1 inhibited proliferation, metastasis and invasion of three...

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Detalles Bibliográficos
Autores principales: Bai, Jian, Zhang, Xue, Hu, Kai, Liu, Bangqing, Wang, Haiyong, Li, Angui, Lin, Feng, Zhang, Lifei, Sun, Xiaolin, Du, Zhenzong, Song, Jianfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190084/
https://www.ncbi.nlm.nih.gov/pubmed/27286455
http://dx.doi.org/10.18632/oncotarget.9866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190084/
https://www.ncbi.nlm.nih.gov/pubmed/27286455
http://dx.doi.org/10.18632/oncotarget.9866

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