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Silencing DNA methyltransferase 1 (DNMT1) inhibits proliferation, metastasis and invasion in ESCC by suppressing methylation of RASSF1A and DAPK
Our previous study showed DNMT1 is up-regulated in esophageal squamous cell carcinoma (ESCC), which is associated with methylation of tumor suppressors. In the current study, we investigate the role of DNMT1 in ESCC. We found silencing DNMT1 inhibited proliferation, metastasis and invasion of three...
Autores principales: | Bai, Jian, Zhang, Xue, Hu, Kai, Liu, Bangqing, Wang, Haiyong, Li, Angui, Lin, Feng, Zhang, Lifei, Sun, Xiaolin, Du, Zhenzong, Song, Jianfei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190084/ https://www.ncbi.nlm.nih.gov/pubmed/27286455 http://dx.doi.org/10.18632/oncotarget.9866 |
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