Inhibition of histone deacetylases induces formation of multipolar spindles and subsequent p53-dependent apoptosis in nasopharyngeal carcinoma cells

Histone deacetylases (HDACs) play crucial roles in the initiation and progression of cancer, offering a promising target for cancer therapy. HDACs inhibitor MGCD0103 (MGCD) exhibits effective anti-tumor activity by blocking proliferation and inducing cell death in malignant cells. However, the molec...

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Detalles Bibliográficos
Autores principales: Yan, Min, Qian, Yuan-min, Yue, Cai-feng, Wang, Zi-feng, Wang, Bi-cheng, Zhang, Wei, Zheng, Fei-meng, Liu, Quentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190087/
https://www.ncbi.nlm.nih.gov/pubmed/27283770
http://dx.doi.org/10.18632/oncotarget.9922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190087/
https://www.ncbi.nlm.nih.gov/pubmed/27283770
http://dx.doi.org/10.18632/oncotarget.9922

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