miR-22 inhibits tumor growth and metastasis by targeting ATP citrate lyase: evidence in osteosarcoma, prostate cancer, cervical cancer and lung cancer

MicroRNAs (miRNAs) are non-coding small RNAs that function as negative regulators of gene expression involving in the tumor biology. ATP citrate lyase (ACLY), a key enzyme initiating de novo lipid synthesis, has been found to be upregulated in cancer cells, and its inhibition causes suppressive effe...

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Detalles Bibliográficos
Autores principales: Xin, Mei, Qiao, Zhiguang, Li, Jing, Liu, Jianjun, Song, Shaoli, Zhao, Xiaoping, Miao, Ping, Tang, Tingting, Wang, Lei, Liu, Weichun, Yang, Xiaodi, Dai, Kerong, Huang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190093/
https://www.ncbi.nlm.nih.gov/pubmed/27317765
http://dx.doi.org/10.18632/oncotarget.10020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190093/
https://www.ncbi.nlm.nih.gov/pubmed/27317765
http://dx.doi.org/10.18632/oncotarget.10020

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