p63β modulates c-Myc activity via direct interaction and regulation of MM1 protein stability

Both p53-related p63 and c-Myc are transcription factors playing key roles in cell proliferation, survival, development and tumorigenesis. In the present study, we identified that MM1, a c-Myc inhibitor, specifically binds to C-termini of p63β (including ΔNp63β and TAp63β). Further study demonstrate...

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Detalles Bibliográficos
Autores principales: Han, Anning, Li, Juan, Li, Yimin, Wang, Yang, Bergholz, Johann, Zhang, Yujun, Li, Chenghua, Xiao, Zhi-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190095/
https://www.ncbi.nlm.nih.gov/pubmed/27341130
http://dx.doi.org/10.18632/oncotarget.10187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190095/
https://www.ncbi.nlm.nih.gov/pubmed/27341130
http://dx.doi.org/10.18632/oncotarget.10187

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