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p63β modulates c-Myc activity via direct interaction and regulation of MM1 protein stability
Both p53-related p63 and c-Myc are transcription factors playing key roles in cell proliferation, survival, development and tumorigenesis. In the present study, we identified that MM1, a c-Myc inhibitor, specifically binds to C-termini of p63β (including ΔNp63β and TAp63β). Further study demonstrate...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190095/ https://www.ncbi.nlm.nih.gov/pubmed/27341130 http://dx.doi.org/10.18632/oncotarget.10187 |