Linking microsomal prostaglandin E Synthase-1/PGE-2 pathway with miR-15a and −186 expression: Novel mechanism of VEGF modulation in prostate cancer

Prostaglandin E-2 (PGE-2) promotes tumor angiogenesis via paracrine secretion of pro-angiogenic growth factors, such as vascular endothelial growth factor (VEGF). Since miRNAs regulate several cell processes, including angiogenesis, we sought to determine whether they would influence PGE-2-induced V...

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Detalles Bibliográficos
Autores principales: Terzuoli, Erika, Donnini, Sandra, Finetti, Federica, Nesi, Gabriella, Villari, Donata, Hanaka, Hiromi, Radmark, Olof, Giachetti, Antonio, Ziche, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190102/
https://www.ncbi.nlm.nih.gov/pubmed/27322147
http://dx.doi.org/10.18632/oncotarget.10051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190102/
https://www.ncbi.nlm.nih.gov/pubmed/27322147
http://dx.doi.org/10.18632/oncotarget.10051

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