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Infiltrating macrophages increase RCC epithelial mesenchymal transition (EMT) and stem cell-like populations via AKT and mTOR signaling

Infiltrating macrophages are a key component of inflammation during tumorigenesis and progression. However, the role of macrophages in renal cell carcinoma (RCC), especially in the stage of RCC malignant progression, is still unclear. Here, we found the macrophages could be recruited more easily int...

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Detalles Bibliográficos
Autores principales: Yang, Zhao, Xie, Hongjun, He, Dalin, Li, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190112/
https://www.ncbi.nlm.nih.gov/pubmed/27283897
http://dx.doi.org/10.18632/oncotarget.9873