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Piezo2 protein: A novel regulator of tumor angiogenesis and hyperpermeability

Angiogenesis is important for invasive tumor growth and metastasis. Its inhibition is a promising tactic for limiting tumor progression. Here, we showed that Piezo2 knockdown led to decreased glioma angiogenesis and reduced vascular hyperpermeability. Piezo2 was highly expressed in tumor endothelial...

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Detalles Bibliográficos
Autores principales: Yang, Hong, Liu, Chang, Zhou, Rong-Mei, Yao, Jin, Li, Xiu-Miao, Shen, Yi, Cheng, Hong, Yuan, Jun, Yan, Biao, Jiang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190124/
https://www.ncbi.nlm.nih.gov/pubmed/27329839
http://dx.doi.org/10.18632/oncotarget.10134