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The progeroid gene BubR1 regulates axon myelination and motor function

Myelination, the process by which oligodendrocytes form the myelin sheath around axons, is key to axonal signal transduction and related motor function in the central nervous system (CNS). Aging is characterized by degenerative changes in the myelin sheath, although the molecular underpinnings of no...

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Detalles Bibliográficos
Autores principales: Choi, Chan-Il, Yoo, Ki Hyun, Qasim Hussaini, Syed Mohammed, Tak Jeon, Byeong, Welby, John, Gan, Haiyun, Scarisbrick, Isobel A., Zhang, Zhiguo, Baker, Darren J., van Deursen, Jan M., Rodriguez, Moses, Jang, Mi-Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191862/
https://www.ncbi.nlm.nih.gov/pubmed/27922816
http://dx.doi.org/10.18632/aging.101032