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Mutational load of the mitochondrial genome predicts pathological features and biochemical recurrence in prostate cancer

Prostate cancer management is complicated by extreme disease heterogeneity, which is further limited by availability of prognostic biomarkers. Recognition of prostate cancer as a genetic disease has prompted a focus on the nuclear genome for biomarker discovery, with little attention given to the mi...

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Detalles Bibliográficos
Autores principales: Kalsbeek, Anton M.F., Chan, Eva F.K., Grogan, Judith, Petersen, Desiree C., Jaratlerdsiri, Weerachai, Gupta, Ruta, Lyons, Ruth J., Haynes, Anne Maree, Horvath, Lisa G., Kench, James G., Stricker, Phillip D., Hayes, Vanessa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191864/
https://www.ncbi.nlm.nih.gov/pubmed/27705925
http://dx.doi.org/10.18632/aging.101044