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An antioxidant specifically targeting mitochondria delays progression of Alzheimer's disease-like pathology

Mitochondrial aberrations are observed in human Alzheimer's disease (AD) and in medical conditions that increase the risk of this disorder, suggesting that mitochondrial dysfunction may contribute to pathophysiology of AD. Here, using OXYS rats that simulate key characteristics of sporadic AD,...

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Detalles Bibliográficos
Autores principales: Stefanova, Natalia A., Muraleva, Natalia A., Maksimova, Kseniya Yi., Rudnitskaya, Ekaterina A., Kiseleva, Elena, Telegina, Darya V., Kolosova, Nataliya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191865/
https://www.ncbi.nlm.nih.gov/pubmed/27750209
http://dx.doi.org/10.18632/aging.101054