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PI3Kɑ inhibition reduces obesity in mice

Partial inhibition of PI3K is one of the best-validated and evolutionary conserved manipulations to extend longevity. The best known health beneficial effects of reduced PI3K are related to metabolism and include increased energy expenditure, reduced nutrient storage, and protection from obesity. We...

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Detalles Bibliográficos
Autores principales: Lopez-Guadamillas, Elena, Muñoz-Martin, Maribel, Martinez, Sonia, Pastor, Joaquin, Fernandez-Marcos, Pablo J., Serrano, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191867/
https://www.ncbi.nlm.nih.gov/pubmed/27816049
http://dx.doi.org/10.18632/aging.101075