Lysine-specific demethylase 1 inhibitor rescues the osteogenic ability of mesenchymal stem cells under osteoporotic conditions by modulating H3K4 methylation

Bone tissue engineering may be hindered by underlying osteoporosis because of a decreased osteogenic ability of autologous seed cells and an unfavorably changed microenvironment in these patients. Epigenetic regulation plays an important role in the developmental origins of osteoporosis; however, fe...

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Detalles Bibliográficos
Autores principales: Lv, Longwei, Ge, Wenshu, Liu, Yunsong, Lai, Guanyou, Liu, Hao, Li, Wenyue, Zhou, Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192052/
https://www.ncbi.nlm.nih.gov/pubmed/28058134
http://dx.doi.org/10.1038/boneres.2016.37

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192052/
https://www.ncbi.nlm.nih.gov/pubmed/28058134
http://dx.doi.org/10.1038/boneres.2016.37

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