Motor neurons derived from ALS-related mouse iPS cells recapitulate pathological features of ALS

Amyotrophic lateral sclerosis (ALS) is a late-onset progressive neurodegenerative disease characterized by the loss of motor neurons in the spinal cord and brain. Mutations in Cu/Zn superoxide dismutase 1 (SOD1) are known to induce ALS. Although many research models have been developed, the exact pa...

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Detalles Bibliográficos
Autores principales: Park, Ju-Hwang, Park, Hang-Soo, Hong, Sunghoi, Kang, Seongman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192071/
https://www.ncbi.nlm.nih.gov/pubmed/27932790
http://dx.doi.org/10.1038/emm.2016.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192071/
https://www.ncbi.nlm.nih.gov/pubmed/27932790
http://dx.doi.org/10.1038/emm.2016.113

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