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Motor neurons derived from ALS-related mouse iPS cells recapitulate pathological features of ALS
Amyotrophic lateral sclerosis (ALS) is a late-onset progressive neurodegenerative disease characterized by the loss of motor neurons in the spinal cord and brain. Mutations in Cu/Zn superoxide dismutase 1 (SOD1) are known to induce ALS. Although many research models have been developed, the exact pa...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192071/ https://www.ncbi.nlm.nih.gov/pubmed/27932790 http://dx.doi.org/10.1038/emm.2016.113 |