Critical Evaluation of Molecular Monitoring in Malaria Drug Efficacy Trials and Pitfalls of Length-Polymorphic Markers

Estimation of drug efficacy in antimalarial drug trials requires parasite genotyping to distinguish new infections from treatment failures. When using length-polymorphic molecular markers, preferential amplification of short fragments can compromise detection of coinfections, potentially leading to...

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Detalles Bibliográficos
Autores principales: Messerli, Camilla, Hofmann, Natalie E., Beck, Hans-Peter, Felger, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Epidemiology and Surveillance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192142/
https://www.ncbi.nlm.nih.gov/pubmed/27821442
http://dx.doi.org/10.1128/AAC.01500-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192142/
https://www.ncbi.nlm.nih.gov/pubmed/27821442
http://dx.doi.org/10.1128/AAC.01500-16

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