PKCɛ switches Aurora B specificity to exit the abscission checkpoint

The ‘NoCut', or Aurora B abscission checkpoint can be activated if DNA is retained in the cleavage furrow after completion of anaphase. Checkpoint failure leads to incomplete abscission and a binucleate outcome. These phenotypes are also observed after loss of PKCɛ in transformed cell models. H...

Descripción completa

Detalles Bibliográficos
Autores principales: Pike, Tanya, Brownlow, Nicola, Kjaer, Svend, Carlton, Jeremy, Parker, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192180/
https://www.ncbi.nlm.nih.gov/pubmed/28004745
http://dx.doi.org/10.1038/ncomms13853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192180/
https://www.ncbi.nlm.nih.gov/pubmed/28004745
http://dx.doi.org/10.1038/ncomms13853

Ejemplares similares