Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy

The development of a tuberculosis (TB) vaccine that induces sterilizing immunity to Mycobacterium tuberculosis infection has been elusive. Absence of sterilizing immunity induced by TB vaccines may be due to delayed activation of mucosal dendritic cells (DCs), and subsequent delay in antigen present...

Descripción completa

Detalles Bibliográficos
Autores principales: Griffiths, Kristin L., Ahmed, Mushtaq, Das, Shibali, Gopal, Radha, Horne, William, Connell, Terry D., Moynihan, Kelly D., Kolls, Jay K., Irvine, Darrell J., Artyomov, Maxim N., Rangel-Moreno, Javier, Khader, Shabaana A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192216/
https://www.ncbi.nlm.nih.gov/pubmed/28004802
http://dx.doi.org/10.1038/ncomms13894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192216/
https://www.ncbi.nlm.nih.gov/pubmed/28004802
http://dx.doi.org/10.1038/ncomms13894

Ejemplares similares