SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization

We currently have limited knowledge of the involvement of long non-coding RNAs (lncRNAs) in normal cellular processes and pathologies. Here, we identify and characterize SNHG5 as a stable cytoplasmic lncRNA with up-regulated expression in colorectal cancer. Depletion of SNHG5 induces cell cycle arre...

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Detalles Bibliográficos
Autores principales: Damas, Nkerorema Djodji, Marcatti, Michela, Côme, Christophe, Christensen, Lise Lotte, Nielsen, Morten Muhlig, Baumgartner, Roland, Gylling, Helene Maria, Maglieri, Giulia, Rundsten, Carsten Friis, Seemann, Stefan E., Rapin, Nicolas, Thézenas, Simon, Vang, Søren, Ørntoft, Torben, Andersen, Claus Lindbjerg, Pedersen, Jakob Skou, Lund, Anders H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192221/
https://www.ncbi.nlm.nih.gov/pubmed/28004750
http://dx.doi.org/10.1038/ncomms13875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192221/
https://www.ncbi.nlm.nih.gov/pubmed/28004750
http://dx.doi.org/10.1038/ncomms13875

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