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Genetic Ablation of Soluble TNF Does Not Affect Lesion Size and Functional Recovery after Moderate Spinal Cord Injury in Mice

Traumatic spinal cord injury (SCI) is followed by an instant increase in expression of the microglial-derived proinflammatory cytokine tumor necrosis factor (TNF) within the lesioned cord. TNF exists both as membrane-anchored TNF (mTNF) and as cleaved soluble TNF (solTNF). We previously demonstrated...

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Detalles Bibliográficos
Autores principales: Ellman, Ditte Gry, Degn, Matilda, Lund, Minna Christiansen, Clausen, Bettina Hjelm, Novrup, Hans Gram, Flæng, Simon Bertram, Jørgensen, Louise Helskov, Suntharalingam, Lujitha, Svenningsen, Åsa Fex, Brambilla, Roberta, Lambertsen, Kate Lykke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192339/
https://www.ncbi.nlm.nih.gov/pubmed/28070141
http://dx.doi.org/10.1155/2016/2684098