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Is There Still Room for Cancer Vaccines at the Era of Checkpoint Inhibitors

Checkpoint inhibitor (CPI) blockade is considered to be a revolution in cancer therapy, although most patients (70%–80%) remain resistant to this therapy. It has been hypothesized that only tumors with high mutation rates generate a natural antitumor T cell response, which could be revigorated by th...

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Detalles Bibliográficos
Autores principales: Karaki, Soumaya, Anson, Marie, Tran, Thi, Giusti, Delphine, Blanc, Charlotte, Oudard, Stephane, Tartour, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192357/
https://www.ncbi.nlm.nih.gov/pubmed/27827885
http://dx.doi.org/10.3390/vaccines4040037