Cargando…

The CD8(+) T Cell-Mediated Immunity Induced by HPV-E6 Uploaded in Engineered Exosomes Is Improved by ISCOMATRIX(TM) Adjuvant

We recently described the induction of an efficient CD8(+) T cell-mediated immune response against a tumor-associated antigen (TAA) uploaded in engineered exosomes used as an immunogen delivery tool. This immune response cleared tumor cells inoculated after immunization, and controlled the growth of...

Descripción completa

Detalles Bibliográficos
Autores principales: Manfredi, Francesco, di Bonito, Paola, Ridolfi, Barbara, Anticoli, Simona, Arenaccio, Claudia, Chiozzini, Chiara, Baz Morelli, Adriana, Federico, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192362/
https://www.ncbi.nlm.nih.gov/pubmed/27834857
http://dx.doi.org/10.3390/vaccines4040042