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The CD8(+) T Cell-Mediated Immunity Induced by HPV-E6 Uploaded in Engineered Exosomes Is Improved by ISCOMATRIX(TM) Adjuvant
We recently described the induction of an efficient CD8(+) T cell-mediated immune response against a tumor-associated antigen (TAA) uploaded in engineered exosomes used as an immunogen delivery tool. This immune response cleared tumor cells inoculated after immunization, and controlled the growth of...
Autores principales: | Manfredi, Francesco, di Bonito, Paola, Ridolfi, Barbara, Anticoli, Simona, Arenaccio, Claudia, Chiozzini, Chiara, Baz Morelli, Adriana, Federico, Maurizio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192362/ https://www.ncbi.nlm.nih.gov/pubmed/27834857 http://dx.doi.org/10.3390/vaccines4040042 |
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