Homologous Prime-Boost Vaccination with OVA Entrapped in Self-Adjuvanting Archaeosomes Induces High Numbers of OVA-Specific CD8(+) T Cells that Protect Against Subcutaneous B16-OVA Melanoma

Homologous prime-boost vaccinations with live vectors typically fail to induce repeated strong CD8(+) T cell responses due to the induction of anti-vector immunity, highlighting the need for alternative delivery vehicles. The unique ether lipids of archaea may be constituted into liposomes, archaeos...

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Detalles Bibliográficos
Autores principales: Stark, Felicity C., McCluskie, Michael J., Krishnan, Lakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192364/
https://www.ncbi.nlm.nih.gov/pubmed/27869670
http://dx.doi.org/10.3390/vaccines4040044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192364/
https://www.ncbi.nlm.nih.gov/pubmed/27869670
http://dx.doi.org/10.3390/vaccines4040044

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