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Tumor Microenvironment Metabolism: A New Checkpoint for Anti-Tumor Immunity

When a T cell infiltrates a tumor, it is subjected to a variety of immunosuppressive and regulatory signals in the microenvironment. However, it is becoming increasingly clear that due to the proliferative and energetically-deregulated nature of tumor cells, T cells also operate at a metabolic disad...

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Detalles Bibliográficos
Autores principales: Scharping, Nicole E., Delgoffe, Greg M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192366/
https://www.ncbi.nlm.nih.gov/pubmed/27929420
http://dx.doi.org/10.3390/vaccines4040046