Co-Administration of Lipid Nanoparticles and Sub-Unit Vaccine Antigens Is Required for Increase in Antigen-Specific Immune Responses in Mice

A vast body of evidence suggests that nanoparticles function as potent immune-modulatory agents. We have previously shown that Merck proprietary Lipid NanoParticles (LNPs) markedly boost B-cell and T-cell responses to sub-unit vaccine antigens in mice. To further evaluate the specifics of vaccine de...

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Detalles Bibliográficos
Autores principales: Thoryk, Elizabeth A., Swaminathan, Gokul, Meschino, Steven, Cox, Kara S., Gindy, Marian, Casimiro, Danilo R., Bett, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192367/
https://www.ncbi.nlm.nih.gov/pubmed/27929422
http://dx.doi.org/10.3390/vaccines4040047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192367/
https://www.ncbi.nlm.nih.gov/pubmed/27929422
http://dx.doi.org/10.3390/vaccines4040047

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