Adenovirus with DNA Packaging Gene Mutations Increased Virus Release

Adenoviruses (Ads) have been extensively manipulated for the development of cancer selective replication, leading to cancer cell death or oncolysis. Clinical studies using E1-modified oncolytic Ads have shown that this therapeutic platform was safe, but with limited efficacy, indicating the necessit...

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Detalles Bibliográficos
Autores principales: Wechman, Stephen L., Rao, Xiao-Mei, McMasters, Kelly M., Zhou, Heshan Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192394/
https://www.ncbi.nlm.nih.gov/pubmed/27999391
http://dx.doi.org/10.3390/v8120333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192394/
https://www.ncbi.nlm.nih.gov/pubmed/27999391
http://dx.doi.org/10.3390/v8120333

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