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Decreased STAT3 Phosphorylation Mediates Cell Swelling in Ammonia-Treated Astrocyte Cultures

Brain edema, due largely to astrocyte swelling, and the subsequent increase in intracranial pressure and brain herniation, are major complications of acute liver failure (ALF). Elevated level of brain ammonia has been strongly implicated in the development of astrocyte swelling associated with ALF....

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Detalles Bibliográficos
Autores principales: Jayakumar, Arumugam R., Curtis, Kevin M., Panickar, Kiran S., Shamaladevi, Nagarajarao, Norenberg, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192428/
https://www.ncbi.nlm.nih.gov/pubmed/27918421
http://dx.doi.org/10.3390/biology5040048