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Critical Function of PRDM2 in the Neoplastic Growth of Testicular Germ Cell Tumors

Testicular germ cell tumors (TGCTs) derive from primordial germ cells. Their maturation is blocked at different stages, reflecting histological tumor subtypes. A common genetic alteration in TGCT is a deletion of the chromosome 1 short arm, where the PRDM2 gene, belonging to the Positive Regulatory...

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Detalles Bibliográficos
Autores principales: Di Zazzo, Erika, Porcile, Carola, Bartollino, Silvia, Moncharmont, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192434/
https://www.ncbi.nlm.nih.gov/pubmed/27983647
http://dx.doi.org/10.3390/biology5040054