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Critical Function of PRDM2 in the Neoplastic Growth of Testicular Germ Cell Tumors
Testicular germ cell tumors (TGCTs) derive from primordial germ cells. Their maturation is blocked at different stages, reflecting histological tumor subtypes. A common genetic alteration in TGCT is a deletion of the chromosome 1 short arm, where the PRDM2 gene, belonging to the Positive Regulatory...
Autores principales: | Di Zazzo, Erika, Porcile, Carola, Bartollino, Silvia, Moncharmont, Bruno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192434/ https://www.ncbi.nlm.nih.gov/pubmed/27983647 http://dx.doi.org/10.3390/biology5040054 |
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