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Metabolomic Profiling of the Effects of Melittin on Cisplatin Resistant and Cisplatin Sensitive Ovarian Cancer Cells Using Mass Spectrometry and Biolog Microarray Technology

In the present study, liquid chromatography-mass spectrometry (LC-MS) was employed to characterise the metabolic profiles of two human ovarian cancer cell lines A2780 (cisplatin-sensitive) and A2780CR (cisplatin-resistant) in response to their exposure to melittin, a cytotoxic peptide from bee venom...

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Detalles Bibliográficos
Autores principales: Alonezi, Sanad, Tusiimire, Jonans, Wallace, Jennifer, Dufton, Mark J., Parkinson, John A., Young, Louise C., Clements, Carol J., Park, Jin Kyu, Jeon, Jong Woon, Ferro, Valerie A., Watson, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192441/
https://www.ncbi.nlm.nih.gov/pubmed/27754384
http://dx.doi.org/10.3390/metabo6040035